Scientists Are Close To Finding Out The Origins of Psoriasis
Psoriasis and eczema are utterly distinct skin diseases despite the fact that their symptoms, red, dry, scaly plaques, are somewhat similar. These two distressing skin condition are often mistaken and confused even by physicians, particularly when they occur simultaneously. Well, it’s quite a rare phenomenon for both Psoriasis and eczema to affect one patient, but still, these cases exist.
German scientists believe that opposing immune system responses that often prompt Psoriasis and eczema flare ups could be the ultimate way to cure these diseases. These scientists assert that further research about Psoriasis and eczema, and their link with the immune system might yield optimistic results, leading to the invention of more targeted and effective treatments. In the July 21 issue of the renowned New England Journal of Medicine, a study about Psoriasis and eczema was published.
About this Research
This research incorporated 3 patients inflicted with both skin diseases, and it was discovered that there was an enormous distinction between the T-cells, some distinctive type of white blood cells that fight infection, in Psoriasis lesions and those found in eczema lesions. Contrary to what other studies have suggested, these findings suggest that in both inflammatory conditions, skin cells are not actually abnormal, but distinct environmental triggers cause these T-cells to migrate to the skin, causing the cell build up.
According to the National Foundation of Psoriasis, the most prevalent auto-immune disease, Psoriasis is affecting almost 7.5 million Americans, and this number is destined to elevate due to genetic and environmental triggers in the near future. According to the American Academy of Allergy, Eczema is an allergic response, which often develops simultaneously with food or asthma allergies. Often at times, eczema is outgrown by adulthood.
In this research, Psoriasis lesions contained huge numbers of so called Th17 and Th1 cells, and eczema lesions contained a large number of Th22 and Th2 cells. This research included 5 more Psoriasis patients, but with nickel skin allergies. The symptoms of Psoriasis and nickel skin allergies prompt like an eczema reaction, and when tested, a similar T-cell number and response to Psoriasis was recorded.
Causes of Psoriasis
This research showed that all eczema lesions harbored the Staphylococcus aureus bacteria, which were not harbored by Psoriasis lesions. Consequently, this confirmed that the T-cells in Psoriasis prompted an innate immune response, while the T-cells in eczema do not. This innate immune response is suspected to be one of the Psoriasis causes. As much as is known about these inflammatory skin conditions, it’s clear that scientists haven’t discovered medication to cure these skin disorders, or even stop their development in predisposed individuals. If these skin specialists pinpoint the exact antigens that stimulate both Psoriasis and eczema, then new treatments might cure these diseases.
[box type="note"]Currently, both the Psoriasis and Eczema treatments available, including topical medication, systematic drugs and phototherapy aim to alleviate these conditions. Psoriasis treatments aim specifically at suppressing the body’s immune system response, slowing down the skin cell growth cycle, hence easing pain, itching and discomfort. Eczema treatments aim at reducing inflammation, itching and pain, and of course, healthy lifestyle transitions help considerably.[/box]