The Journal of Translational Medicine recently published a study that found that drugs used in cancer treatments may be a cure for obesity. Most cancer fighting medications fight the disease by using synthetic peptides to reduce blood supplies in patients. According to this new study, this solution may starve fat cells, which can eventually kill them off. This theory could lead to the introduction of a new drug, which researchers have namedÂ Adipotide.
How does Adipotide work?
Researchers have conducted experimental trials on monkeys to determine the role they may play in weight loss. After a number of obesity medications failed to make it to the marketplace, the study found that existing cancer drugs may actually be the solution many health professionals are looking for. While newer drugs are being considered and medications such as qnexa may be reintroduced by the FDA, these cancer treatment medications may be the solution many people are hoping for.
Dr. Wadih Arap, an oncologist at the M.D. Anderson Cancer Center in Houston and one of the researchers who worked on the project. According to Arap, the weight loss experienced by the monkeys in the clinical study was promising. However, Arap and his colleagues are still unable to explain all of the findings in the study. A number of the species used as test subjects didn’t respond as expected.
Arap said that much more research will need to be conducted before they can determine the appropriate structure of the drug. However, he hope that he and his colleagues will eventually be able to implement a new structure for the drug that will help patients fight obesity.
Safety risks associated with Adipotide?
At the moment, safety is the biggest concern. A few health complications were witnessed in a number of the test subjects, including dehydration, kidney lesions and an unexplained drop in potassium levels. Arap and other researchers realize that more research will need to be conducted before the drug will be able to satisfy FDA requirements.Â Yihai Cao, a microbiologist from Sweden is fascinated by the work. However, he cautions that researchers will need to be able to explain the way Adipotide creates weight loss and what side effects it will lead to.
When will Adipotide be available?
TheÂ M.D. Anderson Cancer Center has started a joint partnership with Arrowhead Research Corp. Anderson hope to get Adipotide to market after completing the R&D process and bringing the drug to the FDA.