Why Lorcaserin And Other Weight Loss Drugs Fail To Deliver

Shortened Lifespan

Sedentary lifestyle, smoking, poor food choices, etc. are habits that are linked to shortened lifespan.  Even if you’re a person with low self-esteem issues, or uses food as an emotional crutch (i.e. eating even when you don’t feel hungry), if you sincerely want to turn  your life around, you’ll do it. Feeling it within the very fiber of your being that you can make your life what you want it to be, you’ll sacrifice to get what you want.

That’s the key to long-term weight loss or any other life success. And you can’t get that in a pill. It must come from within.

BLOOM-DM Trial for Diabetes

[box type=”important”]*Arena did conduct a separate BLOOM study to learn if lorcaserin was safe for patients diagnosed with adult-onset diabetes. This study was named BLOOM -DM where “DM” is the initialism for “diabetes mellitus”. The conclusions of BLOOM-DM are unknown as of the time of the publication of this article.[/box]



  1. FDA Briefing Document NDA 22529 Lorqess (lorcaserin hydrochloride) Tablets, 10 mg, http://www.fda.gov/downloads/AdvisoryCommittees/
  2. 5-HT receptor http://en.wikipedia.org/wiki/5-HT_receptor



I hold a degree from one of the top ranked research universities in the United States. I am the administrator and publisher of Living Fit, Healthy and Happy which is a family-friendly health and wellness website with articles on fitness, anti-aging, obesity, diabetes, eating disorders, cardiovascular health and many other health related issues. Publishing fitness and healthy living blogs is my way of getting the word out to the public about the benefits of a healthy lifestyle. So on Living Fit, Healthy and Happy I write articles using the pen name "healthy_blogging". I also re-publish the articles of other authors whom I deem to have scientific merit and serve the public interest. In my free time, I enjoy physical fitness, outdoor activities, reading of fiction and nonfiction material, listening to music and spending time with family and friends.

12 thoughts on “Why Lorcaserin And Other Weight Loss Drugs Fail To Deliver

  • November 18, 2010 at 4:11 pm

    Lactulose is a potent laxative. There will be diarrhea, but that is to be expected. Normal side effects are bloating, belly cramps, etc. For patients in advanced kidney failure, things get a bit tricky, as diarrhea means excretion of potassium. Because of that hypokalemia )low potassium) and hypernatremia (high sodium) can ensue. These electrolytes need to be measured carefully in such patients and whoever prescribed the lactulose must know that patient has these health problems. Hope that helps…

  • October 28, 2010 at 12:23 pm

    Hello Jarret and Doug,

    I’m excited by all the buzz that my article has been generating. It’s an important topic and I’m happy for the opportunity to guest post here and that so many people find the article informative.

    I agree that Arena failed to because they only looked at one aspect of obesity. Until the pharmaceutical industry helps consumers address the root causes of the problem, they will never be successful in helping the masses sustain long term healthy body weight.


  • October 27, 2010 at 8:37 am

    Joseph, thanks for the great article on weight loss pills and Locaserin, in particular. 370 retweets is definitely the most we’ve ever seen here at Hive Health Media.

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  • October 26, 2010 at 7:51 am

    One significant hurdle facing any and all obesity drug manufacturers is that obesity is a multi-faceted problem

    Brain chemistry, hormones, genetics, epigenetics, lifestyle, social pressure, advertising, etc….

    So, when a drug like Lorcaserin takes a focused approach (serotonin) to solve a multi-faceted problem, I believe that they are doomed to failure.


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